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Uji diagnostik uji antigen sars-cov-2 pada pemeriksaan laboratorium covid-19: Studi kasus di RS Beriman Kota Balikpapan, Indonesia

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Pages 55-61

Abstract

The performance characteristics of the rapid SARS-CoV-2 antigen detection test should be evaluated and compared with the reverse transcription-polymerase chain reaction (RT-PCR) assay as the standard for diagnosis of COVID-19 cases. This research is a descriptive observational study with a cross-sectional research design. Secondary data from suspected COVID-19 patients who were examined for SARS-CoV-2 antigen and the results of RT-PCR in January - April 2021 at the Beriman Hospital of Balikpapan City, which was 336 samples. Based on the results of the study, the number of samples with an antigen-positive test for SARS-CoV-2 and a positive RT-PCR result was 114 (33.93%), the number of samples with an antigen-positive test for SARS-CoV-2 and a negative RT-PCR result was 2 (0.6%), the number of samples with positive SARS-CoV-2 antigen-negative test results and RT-PCR was 23 (6.85%), and the number of samples with SARS-negative antigen-negative test and RT-PCR results CoV -2 and negative PCR were 197 (58.63%). The result of the SARS-CoV-2 antigen sensitivity was 83.21%, while the specificity was 98.99%. The accuracy value of the SARS-CoV-2 antigen is 92.56%. The rapid antigen test used in this study has sensitivity and specificity as recommended by WHO, so it is suitable for use for COVID-19 laboratory tests.

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References

  • Susilo A., Rumende C. M., Pitoyo C. W., Santoso W. D., Yulianti M., Herikurniawan, Sinto R., Singh G., Nainggolan L., Nelwan N. J., Chen L. K., Widhani A., Wijaya E., Wicaksana B., Maksum M., Annisa F., Jasirwan C. O. M YE. Coronavirus Disease 2019: Tinjauan Literatur Terkini. J Penyakit dalam Indones. 2020;7(1):45. doi:10.7454/jpdi.v7i1.415
  • WHO. Getting Your Workplace Ready for COVID-19. Published online 2020.
  • WHO. Saran Penggunaan Tes Imunodiagnostik di Fasyankes (Point of Care) untuk COVID-19. Published online 2020.
  • WHO. Diagnostic testing for SARS-CoV-2. Published online 2020.
  • Direktorat Jenderal Pencegahan dan Pengendalian Penyakit (P2P). Pedoman Pencegahan Dan Pengendalian Corona Virus Diseases 19 (COVID-19).; 2020.
  • Putra, I. W. G Artawan Eka, Sutarga, I. M., Kardiwinata, M. P., Suariyani, N. L. P., Septarini, N. W., Subrata IM. Modul Penelitian Uji Diagnostik Dan Skrining. Progr Stud Kesehat Masy Fak Kedokt Univ Udayana. Published online 2016:45. https://simdos.unud.ac.id/uploads/file_pendidikan_1_dir/d204d4a5ad0870a0965416e671a38791.pdf
  • Chaimayo C., Kaewnaphan B., Tanlieng N., Athipanyasilp N., Sirijatuphat R., Chayakulkeeree M., Angkasekwinai N., Sutthent R., Puangpunngam N., Tharmviboonsri T., Pongraweewan O., Chuthapisith S., Sirivatanauksorn Y., Kantakamalakul W. HN. Rapid SARS-CoV-2 antigen detection assay in comparison with real-time RT-PCR assay for laboratory diagnosis of COVID-19 in Thailand. Virol J. 2020;17(1). doi:10.1186/s12985-020-01452-5
  • RI K. Angka Kesembuhan COVID-19 Indonesia di Atas Rata-rata Dunia. Published online 2020. Diakses tanggal 20 Februari 2021 pada www.kemkes.go.id
  • RI. K. Pedoman Tata Laksana COVID-19. Published online 2020. Diakses tanggal 23 Januari 2021 pada www.COVID-19.go.id
  • Putra IAE, Sutarga I, Kardiwinata M, Suariyani N, Septarini N, Subrata I. Modul Penelitian Uji Diagnostik Dan Skrining. Progr Stud Kesehat Masy Fak Kedokt Univ Udayana. Published online 2016:45.
  • Hewajuli. D. A. and Dharmayanti N. The Advance of Technology of Reverse Transcriptase-Polymerase Chain Reaction in Identifying the Genome of Avian Influenza and Newcastle Diseases. Indones Bull Anim Vet Sci. 2014;24(1):16–29. doi:10.14334/wartazoa.v24i1.1022
  • Guo Y. R., Cao Q. D., Hong Z. S., Tan Y. Y., Chen S. D., Jin H. J., Tan K. S., Wang D. Y. YY. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak- A n update on the status. Mil Med Res. Published online 2020. doi:10.1186/s40779-020-00240-0
  • [Mertens P., De Vos N., Martiny D., Jassoy C., Mirazimi A., Cuypers L., Van den Wijngaert S., Monteil V., Melin P., Stoffels K., Yin N., Mileto D., Delaunoy S., Magein H., Lagrou K., Bouzet J., Serrano G., Wautier M., Leclipteux T., Van Ranst M., Vandenbe VO. Development and Potential Usefulness of the COVID-19 Ag Respi-Strip Diagnostic Assay in a Pandemic Context’. Front Med. Published online 2020. doi:10.3389/fmed.2020.00225
  • RI K. 13,2 Persen Pasien COVID-19 yang Meninggal Memiliki Penyakit Hipertensi. Published online 2020. Diakses tanggal 21 Januari 2021 pada www.kemkes.go.id
  • WHO. Panduan Interim Deteksi Antigen Dalam Diagnosis Infeksi SARS-CoV-2 Menggunakan Imunoasai Cepat. Published online 2020.
  • Qin C, Zhou L, Hu Z, Zhang S, Yang S, Tao Y et al. Dysregulation of immune response in patients with COVID-19 in Wuhan, China. Clin Infect Dis. Published online 2020. doi:10.1093/ cid/ciaa248
  • RRC KKN. Panduan Menghadapi Penyakit Virus Corona 2019 Model RRC: Pencegahan, Pengendalian, Diagnosis Dan Manajemen. (NTT D ke BI oleh FA, ed.).; 2020.
  • Lippi, G., Simundic, A.-M., & Plebani M. Potential preanalytical and analytical vulnerabilities in the laboratory diagnosis of coronavirus disease 2019 (COVID-19). Clin Chem Lab Med. Published online 2020. doi:https://doi.org/10.1515/cclm-2020-0285
  • WHO. WHO Coronavirus Disease (COVID-19) Dashboard. Published online 2021.
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How to Cite This

Hartantoro, D., Nuryati, A., & Nuryani, S. (2021). Uji diagnostik uji antigen sars-cov-2 pada pemeriksaan laboratorium covid-19: Studi kasus di RS Beriman Kota Balikpapan, Indonesia. PUINOVAKESMAS, 2(2), 55–61. https://doi.org/10.29238/puinova.v2i2.1171

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