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Dampak Paparan Gas Hidrogen Sulfida (H2S) Terhadap Kadar Gula Darah Pada Pekerja Pabrik Crumb Rubber Di Kota Palembang Sumatera Selatan

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Pages 66-74

Abstract

Hydrogen sulfide (H2S) is one of the pollutants in the air. One of the industries that cause H2S odor is the natural rubber industry. Exposure to H2S has an impact on increasing blood sugar levels. High blood sugar levels can lead to diabetes. Diabetes mellitus can increase risks such as myocardial infarction, stroke, kidney failure, lower extremity amputation and vision loss. Based on this, the authors are interested in studying the impact of exposure to H2S gas on blood glucose levels in crumb rubber factory workers in the city of Palembang. This study is a cross-sectional analysis. The study was conducted at the crumb rubber factory in Palembang City in March 2020. The sampel this study with a total of 215 workers. Data analysis using chi square with p <0.05. The results of the analysis concluded that there was no relationship between age (pV=0.758), gender (pV=0.532), smoking (pV=1,000), body mass index (pV=0.571), exposure to H2S gas (pV=0.772) with blood glucose levels. This is probably because the main role of H2S in the pancreas is to protect pancreatic B cells and regulate insulin secretion. H2S can protect pancreatic b cells in the following three ways: (1) reducing ROS production; (2) inhibits the expression of thioredoxin binding protein-2-a redox protein associated with diabetes that promotes apoptosis; and (3) increased GSH content, all of which reduce oxidative stress damage.

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References

  • Park B, Kim S, Park S, Kim M, Kim TY, Park H. Development of Multi-Item Air Quality Monitoring System Based on Real-Time Data. Appl Sci. 2021;11(20):9747.
  • Oktriyedi F, Dahlan MH, Irfannuddin, Ngudiantoro. Impact of latex coagulant various from rubber industry in South Sumatera. AIP Conf Proc. 2021;2344(March).
  • Promnuan K, O-Thong S. Biological Hydrogen Sulfide and Sulfate Removal from Rubber Smoked Sheet Wastewater for Enhanced Biogas Production. Energy Procedia [Internet]. 2017;138:569–74. Available from: https://doi.org/10.1016/j.egypro.2017.10.161
  • Menteri Ketenagakerjaan Republik Indonesia. Keputusan Menteri Ketenagakerjaan Republik Indonesia No.94 Tahun 2018 tentang Penetapan Standar Kompetensi Kerja Nasional Indonesia Kategori Pengolahan Golongan Pokok Industri Karet, Barang Dari Karet Dan Plastik Bidang Industri Karet Remah (Crumb Rubber) [Internet]. Jakarta; 2018. p. 1–159. Available from: kemenperin.go.id › kompetensi › download%0A
  • Balittri. Petani di Babel Masih Menggunakan Tawas sebagai Koagulan Lateks. 2014. p. 1–5.
  • Solichin M, Anwar A. Deorub K Pembeku Lateks dan Pencegah Timbulnya Bau Busuk Karet. Tabloid Sinar Tani. 2006;2.
  • Pajarito BB, Castañeda KC, Jeresano SDM, Repoquit DAN. Reduction of Offensive Odor from Natural Rubber Using Zinc-Modified Bentonite. Adv Mater Sci Eng. 2018;2018.
  • Tekasakul P, Tekasakul S. Environmental Problems Related to Natural Rubber Production in Thailand. J Aerosol Res. 2006;21(2):122–9.
  • Rattanapan C, Suksaroj TT, Chumpikul J, Choosong T. Health Risk Assessment of Hydrogen Sulfide Exposureamong Workers in a Thai Rubber Latex Industry. Environ Asia. 2014;7(1):104–11.
  • Oktriyedi F, Irfannuddin, Ngudiantoro, Dahlan MH, Nurhayati. Characteristics of Polluters In The Working Environment of PT X Palembang City. Pollut Res. 2021;40(2):438–43.
  • Gapkindo. Members of Gapkindo, South Sumatra Branch [Internet]. 2020 [cited 2020 Jan 10]. Available from: https://www.gapkindo.org/cabang/92-south-sumatera
  • Agency for Toxic Substances and Disease Registry. Toxicological Profile for Hydrogen Sulfide and Carbonyl Sulfide. Agency Toxic Subst Dis Regist Rep [Internet]. 2016;(November). Available from: https://www.atsdr.cdc.gov/toxprofiles/tp114.pdf
  • Oktriyedi F, Irfannuddin, Ngudiantoro, Dahlan MH. Polluting Factors in Rubber Plants that Interfere with Health. Maj Kedokt Sriwij. 2021;53(2 April):42–8.
  • Dewi RS, Rahayu L, Made NI, Sandhiutami DWI, Atika I. Efek Penurunan Kadar Glukosa Darah Rebusan Asparagus ( Asparagus offi cinalis L .) pada Mencit yang Diinduksi Aloksan ( Blood Glucose Level Reduction Eff ect of Boiled Asparagus ( Asparagus offi cinalis L .) in Mice Induced by Alloxan ). J Ilmu Kefarmasian Indones. 2021;19(1):56–61.
  • Ahn J, Yang Y. Factors associated with poor glycemic control amongst rural residents with diabetes in Korea. Healthc. 2021;9(4):1–11.
  • Tsimihodimos V, Gonzalez-Villalpando C, Meigs JB, Ferrannini E. Hypertension and Diabetes Mellitus Coprediction and Time Trajectories. Hypertension. 2018;71(3):422–8.
  • Rahayuningrum ET. G ULA D ARAH P ADA P ASIEN D IABETES M ELITUS D I U NIT R AWAT J ALAN D I R SUD D R . L OEKMONO H ADI K UDUS. 2020;11(2):272–9.
  • Rudi A, Kwureh HN. Faktor Risiko Yang Mempengaruhi Kadar Gula Darah Puasa Pada Pengguna Layanan Laboratorium. J Ilm Ilmu Kesehat Wawasan Kesehat. 2017;3(2).
  • Berkat, Saraswati LD, Muniroh M. Faktor-Faktor Yang Berhubungan Dengan Kadar Gula Darah Pada Penderita Diabetes Melitus Tipe 2 Di Rsud K.R.M.T Wongsonegoro Semarang. J Kesehat Masy. 2018;6(1):200–6.
  • Roza M. Faktor-Faktor Yang Berhubungan Dengan Kadar Glukosa Darah Sewaktu Pasien DM Tipe 2. J Keperawatan. 2015;9(2):352–61.
  • Yi S, Yi J, Ohrr H. Total cholesterol and all-cause mortality by sex and age?: a prospective cohort study among 12 . 8 million adults. Sci Rep [Internet]. 2019;(May 2018):1–10. Available from: http://dx.doi.org/10.1038/s41598-018-38461-y
  • Anagnostis P, Stevenson JC, Crook D, Johnston DG, Godsland IF. Effects of menopause, gender and age on lipids and high-density lipoprotein cholesterol subfractions. Maturitas [Internet]. 2015;1–7. Available from: http://dx.doi.org/10.1016/j.maturitas.2015.02.262
  • McGuinn LA, Schneider A, McGarrah RW, Ward-Caviness C, Neas LM, Di Q, et al. Association of long-term PM 2.5 exposure with traditional and novel lipid measures related to cardiovascular disease risk. Environ Int [Internet]. 2019;122(November):193–200. Available from: https://doi.org/10.1016/j.envint.2018.11.001
  • Menteri Negara Lingkungan Hidup. Baku Tingkat Kebauan. 1996. p. 40–2.
  • Minister of Manpower. Peraturan Menteri Tenaga Kerja dan Transmigrasi Nomor Per.13/Men/X/2011 Tentang Nilai Ambang Batas Faktor Fisika dan Faktor Kimia di Tempat Kerja Tahun 2011. Menteri Tenaga Kerja Dan Transm. 2011;1–48.
  • Susilawati, Rahmawati R. Hubungan Usia, Jenis Kelamin dan Hipertensi dengan Kejadian Diabetes Mellitus Tipe 2 di Puskesmas Tugu Kecamatan Cimanggis Kota Depok. Arkesmas. 2021;6(1):15–22.
  • Mildawati, Diani N, Wahid A. Hubungan Usia, Jenis Kelamin dan Lama Menderita Diabetes dengan Kejadian Neuropati Perifer Diabateik. Caring Nurs J. 2019;3(2):31–7.
  • Masruroh E-. Hubungan Umur Dan Status Gizi Dengan Kadar Gula Darah Penderita Diabetes Melitus Tipe Ii. J Ilmu Kesehat. 2018;6(2):153.
  • Komariah K, Rahayu S. Hubungan Usia, Jenis Kelamin Dan Indeks Massa Tubuh Dengan Kadar Gula Darah Puasa Pada Pasien Diabetes Melitus Tipe 2 Di Klinik Pratama Rawat Jalan Proklamasi, Depok, Jawa Barat. J Kesehat Kusuma Husada. 2020;(Dm):41–50.
  • Musdalifah, Setiyo Nugroho P. Hubungan Jenis Kelamin dan Tingkat Ekonomi dengan Kejadian Diabetes Melitus di Wilayah Kerja Puskesmas Palaran Kota Samarinda Tahun 2019. Borneo Student Res [Internet]. 2020;1(2):2020. Available from: https://journals.umkt.ac.id/index.php/bsr/article/view/483
  • Rita N. Hubungan Jenis Kelamin, Olah Raga Dan Obesitas Dengan Kejadian Diabetes Mellitus Pada Lansia. Jik- J Ilmu Kesehat. 2018;2(1):93–100.
  • Tigauw JH, Kapantow NH, Sondakh RC. Hubungan antara Jenis Kelamin dengan kadar Adiponektin pada Penderita Diabetes Melitus Tipe 2 di Kota Manado. Fkm Unsrat. 2014;1:1–7.
  • Latifah N, Nugroho PS. Hubungan Stres Dan Merokok Dengan Kejadian Diabetes Melitus Di Wilayah Kerja Puskesmas Palaran Kota Samarinda Tahun 2019. Hub Stres Dan Merokok Dengan Kejadian Diabetes Melitus Di Wil Kerja Puskesmas Palaran Kota Samarinda Tahun 2019 [Internet]. 2020;1(2):1243–8. Available from: https://journals.umkt.ac.id/index.php/bsr/article/view/513/440
  • Haiti M. Active and Passive Smokers With Blood Glucose Levels. Perokok Aktif Dan Pasif Dengan Kadar Glukosa Darah. 2018;1–4.
  • Wiatma DS, Amin M. Hubungan Merokok Dengan Kadar Glukosa Darah Mahasiswa Fakultas Hukum Universitas Islam Al-Azhar Tahun 2019. J Kedokt. 2019;4(2):63.
  • Suryanti SD, Raras AT, Dini CY, Ciptaningsih AH. Hubungan Indeks Masa Tubuh Dengan Kadar Gula Darah Puasa Pada Pasien Diabetes Melitus Tipe 2. Poltekita J Ilmu Kesehat. 2019;13(2):86–90.
  • Wati DA. Hubungan Indeks Massa Tubuh (IMT) dengan Kadar Glukosa Darah Sewaktu pada Kelompok Senam Lansia Wanita di Aisyah Medical Center (AMC). J Gizi Aisyah. 2019;3(1):19–23.
  • Adnan M, Mulyati T, Isworo JT. Hubungan Indeks Massa Tubuh (IMT) Dengan Kadar Gula Darah Penderita Diabetes Mellitus (DM) Tipe 2 Rawat Jalan Di RS Tugurejo Semarang. J Gizi. 2013;2(April):18–25.
  • Ahmad FUD, Sattar MA, Rathore HA, Abdullah MH, Tan S, Abdullah NA, et al. Exogenous hydrogen sulfide (H 2S) reduces blood pressure and prevents the progression of diabetic nephropathy in spontaneously hypertensive rats. Ren Fail. 2012;34(2):203–10.
  • Chen HJ, Ngowi EE, Qian L, Li T, Qin YZ, Zhou JJ, et al. Role of Hydrogen Sulfide in the Endocrine System. Front Endocrinol (Lausanne). 2021;12(July):1–9.
  • Comas F, Moreno-Navarrete JM. The impact of h2s on obesity-associated metabolic disturbances. Antioxidants. 2021;10(5):1–23.
  • Untereiner A, Wu L. Hydrogen Sulfide and Glucose Homeostasis: A Tale of Sweet and the Stink. Antioxidants Redox Signal. 2018;28(16):1463–82.
  • Wu L, Yang W, Jia X, Yang G, Duridanova D, Cao K, et al. Pancreatic islet overproduction of H2S and suppressed insulin release in Zucker diabetic rats. Lab Investig. 2009;89(1):59–67.
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How to Cite This

Oktriyedi, F., Irfannuddin, I., Ngudiantoro, N., & Dahlan, M. H. . (2021). Dampak Paparan Gas Hidrogen Sulfida (H2S) Terhadap Kadar Gula Darah Pada Pekerja Pabrik Crumb Rubber Di Kota Palembang Sumatera Selatan. Sanitasi: Jurnal Kesehatan Lingkungan, 14(2), 66–74. Retrieved from https://e-journal.poltekkesjogja.ac.id/index.php/Sanitasi/article/view/1201

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